STEP 1: Make sure your macOS software version is v10.13.6 (17G14033). To download and install the drivers, follow the steps below: Model identifier should be Mac Pro 5,1 (2010) Quadro K5000 for Mac, Quadro 4000 for Mac If you have the previously recalled 387.10.10.15.15.108 Web Driver installed, it is necessary that you uninstall that driver completely and replace it with this. IMPORTANT: This graphics driver update contains a security improvement in the NVIDIA Driver Manager preference panel via a new Developers Tab. Do not launch any other applications until the process is complete and the system has been rebooted. The installer also requires rebooting the system after the installation process. Do not manually close System Preferences until after clicking Allow in the Security & Privacy Preferences, later in the process. The installer requires System Preferences to be launched during the installation process. In order to run macOS Applications that leverage the CUDA architecture of certain NVIDIA graphics cards, users will need to download and install the NVIDIA CUDA 10.1 Driver 418.163 for macOS.
